4 LIFE RESEARCH

RioVida™

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                                          How is Riovida Different?

If a product is promoted honestly and the product has real value in the market place of competition, then the consumer response to the product will produce long-term success.

1. Generally, new products on the market contain just another nutrient similar to other nutrients already on the market. The function of these newly commercialized nutrients are similar to other nutrients already saturating our industry. In network marketing, introducing a nutrient that the public isn't well informed with, can create excitement for awhile. Once the public learns that the nutrient is just another herb or phytonutrient among many that do the same things, attrition is the result.

For example, the nutrient Xanthones found in the mangosteen fruit is promoted for its anti-inflammatory properties. Xanthones are promoted for their ability to inhibit the COX-2 enzyme that causes inflammation. There are literally dozens of other phytonutrients that fight inflammation, inhibit the COX-2 enzyme, and some do it better, such as the curcumin, nettle leaf, ginger root, boswella, DHA fatty acid (fish oil), GLA (gamma linolenic acid) and even vitamin E.

Your body uses inflammation as a weapon in its fight to keep you well. Inflammation is good when it is controlled properly. There are a number of body enzymes and body chemicals that can create inflammation such as:

· TNF-a tumor necrosis factor-alpha
· IL-6 interleukin-6
· IL-1(b) interleukin-1 beta
· IL-8 interleukin-6
· Lipoxygenase

Nutrients like Xanthones, control inflammation by inhibiting it. Riovida contains transfer factors by both inhibiting certain factors and regulating several others. Transfer factors will allow useful inflammation to do its job while down-regulating harmful inflammation. As you can see there is a major difference.
Riovida is different than any other health beverage. Riovida contains certain nutrients that perform certain functions that no other nutrient can do. Riovida not only contains the best antioxidants and nutrients on the market but contains a one-of-a-kind nutrient, transfer factor. Transfer factor is the flagship ingredient in Riovida. Transfer factor isn't a vitamin, mineral, amino acid, phytonutrient or any known nutrient. We only call it a nutrient for lack of a better word. Transfer factors are unlike any known nutrient.
Government Agency recommends to Hospitals and Doctors

4Life'sÔ Transfer Factor is the only nutritional product that a government agency has recommended to be used on patients in hospitals, by doctors. After ten clinical studies on actual patients, the Russian Ministry of Health (like the FDA in the USA ) sent a 32-page report to hospitals and doctors in Russia, encouraging the use of Transfer Factor for patients.
In one of these studies involving actual patients, two groups were with individuals suffering from hepatitis C were studied. One group was given interferon and the other 4Life's™ Transfer Factor. Treatment with interferon can cost up to $15,000 per year. Transfer Factor performed in only two weeks as well as interferon did in three months. Other studies involved patients with AID’s, skin conditions and blood infections, etc. The doctors and scientists were astounded at the performance of Transfer Factor. These independent scientists made the statement, that no other nutritional product in the world can do what Transfer Factor can do.
Regulate your health

Transfer factors are regulators of your health. You already have transfer factors in your body. These transfer factors regulate a great number of other immune system cells and body chemicals. Transfer factors also regulate the body’s production of antioxidants. Transfer factors are involved in or influence a number of body functions and processes, such as; the immune system, detoxification, cellular rejuvenation, anti-oxidation and the aging process.
Transfer factors store information and use that information to regulate your health. Transfer factors use amino acids to store this information. The amino acids change sequences like the alphabet. Think about how many words twenty-six letters of the alphabet can spell. There are 44 amino acids in a transfer factor.
An example of how transfer factor works can be observed when you come in contact with a chicken pox germ. The first time you come in contact with the chicken pox germ, you develop chicken pox. Throughout your life, you come in contact with the chicken pox germ again and again but only develop the chicken pox disease once. Why?
A Transfer factor is like a little brain

Transfer factors are like little brains floating throughout your body. Transfer factors store information about the characteristics of the chicken pox germ. When the germ re-enters the body, transfer factors recognize these germs and communicate to other immune system cells to kill the germ. Because of this, you don't develop chicken pox a second time.

Everyday your body develops mutated cells, which if not destroyed, develop into cancer cells. How does the body recognize these mutations? Transfer factors are involved in the recognition process and signal killer cells to destroy the mutated cells.
I will share another example of how transfer factors work. Harmless particles enter and pass through your body everyday. Sometimes your immune system doesn't properly recognize these particles, such as pollen, dust etc., as harmless and in turn reacts to them as if they are harmful. The result is allergies. Transfer factors are involved in regulating this process. When transfer factors in your body do their job, your immune system will recognize the harmless particles for what they are and will not react to them, letting them pass through your body.

Riovida is packed full of antioxidants with one of the highest ORAC values in the industry. Antioxidants are very important in our battle against disease and pre-mature aging. There are other good products on the market along with Riovida that provide a rich mixture of antioxidants. However, only Riovida contains transfer factors, which regulate the body's production of antioxidants.

This is a very important factor in our battle against pre-mature aging and disease. Antioxidants that are consumed must make their way through a dysfunctional digestive system, through a clogged circulatory system, through collapsed capillaries and through cell membranes that are hardening.
Transfer factors increase the actual production of natural antioxidants from within the cell. This is a key to staying well and younger, functionally. Within the cell is mitochondria. Mitochondria are small factors that produce cellular energy that allows each cell, gland, organ, etc. to do their jobs. The mitochondria process, manufactures energy, as a byproduct, creating millions of free radicals. Free radicals damage cells. Increasing the production of antioxidants from within the cells, assures us that we are experiencing the greatest possible protection.


1. Acai juice (ah-sigh-ee)
The Acai berry was selected as one of the ingredients in our Riovida formulation because it is one of the world's richest sources of nutrition and antioxidants. The Acai berry can only be found in the Amazon Rain Forest. For centuries, the indigenous people of Brazil 's Northern Amazon region have revered this legendary berry as a source of healing for numerous ailments. It has been referred to as the “fruit of the Gods,” because of its healing properties.

Modern Science has now validated the remarkable wellness benefits of the Acai fruit. Recently, TV's Oprah Winfrey hired the best nutritionists that money can buy. This nutritionist, Dr. Nicholas Perricone, rated the Acai berry as the #1 super food in the world.

Acai Berry is also known to have the following effects: Anti-inflammatory, anti-bacterial, anti-oxidant, anti-mutagenic, and cardiovascular system.
The following are a number of benefits of the Acai berry:
· Delivers great energy
· Provides better sleep
· Improved digestion
· Improved Mental Focus
· The Acai has more proteins then an average egg
· The Acai berry has essential minerals such as iron, potassium, phosphorus, calcium, vitamin B1 (Thiamin), vitamin B2 (Riboflavin), vitamin B3 (Niacin), vitamin C, and vitamin E. It is much like consuming a multi-vitamin.
· Improved sexual function
· The Acai berry has been shown to have up to 33 times the Anthocyanins than red wine grapes.
· The primary anthocyanin in .Acai is cyanidin-3 glucoside (1), Cyanidin-3- glucoside has been found to be 3.5 times stronger than Trolox (vitamin E analogue) and the predominate anthocyanin found in red wine (nalvadin-3-glucoside) in an ORAC analysis (measure of antioxidant capacity) (2).
· Anthocyanins have been found to "exhibit numerous potential therapeutic effects including treatment of diabetic retinopathy and fibrocystic disease of the breast in humans." (2). "Other potential physiological effects of anthocyanins include radiation ¬protective, chemoprotective, vasoprotective and anti-inflammatory agents." (2)
· The Acai berry has high levels of fiber that are good for colon health and healthy glucose levels.
· The Acai has two essential fatty acids known as Omega 6 (Linoleic acid) and Omega 9 (Oleic acid). Research shows that these fatty acids maintain normal cholesterol levels.
· The Acai contains a rich source of antioxidants that help keep the arterial lining flexible and reduce the oxidation of cholesterol which is important for better blood circulation and a healthy cardio vascular system.
· An almost perfect essential amino acid complex in conjunction with valuable trace minerals, vital to proper muscle contractions and regeneration.
· Very low Sugar content for a fruit
· Cleansing and Detoxing your body
· Boost your Immune System
· The fatty acid ratio of the Acai berry resembles that of olive oil, which is thought to be a contributing factor to the low incidence of heart disease in Mediterranean populations (1, 5). Recently, scientists found the fatty acids in olive oil may stop the expression of a gene that causes breast cancer.
· 60% Oleic (Omega 9) a monounsaturated, essential fatty acid, helps lower LDL (harmful cholesterol) while maintaining HDL, (beneficial cholesterol) levels (5). 12% Linoleic (Omega 6) a polyunsaturated, essential fatty acid, has been found to lower both LDL and manage HDL levels (5).
· Fatty acids aid in the transport and absorption of fat-soluble vitamins ie, Vitamins A, E, D, and K(3)
· Contains Plant Sterols which are components of plant cell membranes providing numerous benefits to the human body, namely the reduction of blood plasma cholesterol (5). Sterols are currently being used to treat symptoms associated with BP.
Elderberry
The Elderberry extract has traditionally been used topically for infections, inflammations of the skin and swelling. The action of Elderberry extract is that it prevents viral hemaglutinin or the process of invading cells using their spike-like projections to introduce its enzyme into healthy cell membranes. The viral enzyme is also neutralized in the presence of elderberry extract.

It can be made into tea and has traditionally been used to soothe sore throats, and make a person feel much better when he is suffering from the cold or flu conditions, and relieves respiratory distress. The flowers are infused for fevers, eruptive skin conditions such as measles and severe bronchial and lung problems. Elderberry tips tone the mucous linings of the nose and throat, increasing their resistance to infections. They are often prescribed for chronic congestion, allergies, ear infections and candidiasis Elder flowers are a mild astringent and used to help relieve the symptoms of eczema, psoriasis and acne.These berries also have laxative and diuretic properties. Elder berries contain a considerable amount of vitamins A, B and C and one of the richest sources of anthocyanins.

Anthocyanins stimulate the body's immune response by promoting the production of lymphocytes that act as a second line of defense against foreign cells. The berries also contain flavanoids, tannins, carotenoids and amino acids which assist in relief from sore throats and the common cold. Flavonoids, including quercetin, are believed to account for the therapeutic actions of the elderberry flowers and berries.

These flavanoids include anthocyanins that are powerful antioxidants and protect cells against damage, according to test tube studies. According to laboratory research, an extract from the leaves, combined, inhibits the influenza virus and herpes simplex virus. The effect on influenza by syrup made from the berries of the black elderberry has been studied in a small double-blind trial. People receiving an elderberry extract (2 tablespoon [30 ml] per day for children, 4 tablespoons, ([60 ml] per day for adults) appeared to recover faster than did those receiving a placebo. Animal studies have shown the flowers to have anti-inflammatory properties. These actions have not been verified in human clinical trials.
Blueberries

Blueberries have 2,400 numerous vitamins, antioxidants, minerals Blueberries are associated with verous health benefits including protection against urinary-tract infections, cancer, age-related health conditions, earth disease and brain damage from strokes, yet current per capita consumption is just our cups a year, an amount that is just one-sixth the amount of strawberries consumed.
In a previous study on lab rats, old rats fed a diet rich in blueberries grew neurons, which means the blueberries may play a role in reversing age-related short-term memory loss. While the results haven’t been replicated in human trials, another study on lab rats is further investigating the effects of blueberries.

Pomegranate

Research shows that daily consumption of the antioxidants in Pomegranate Juice may offer:
Heart Health - Studies in laboratory mice have show that consumption of Pomegranate Juice reduced the buildup of plaque in the lining of the inner artery. In fact, it reduced the size of atherosclerotic lesions by 44% - Aviram, M. et al, American Journal of Clinical Nutrition 2000, 71:1062
Reduction of LDL (bad) Cholesterol - Studies in the American Journal of Clinical Nutrition have shown that the antioxidants found in Pomegranates reduce the LDL oxidation in mice, and help to lower blood pressure in hypertensive humans.

Neutralize Free Radicals - Pomegranates contain antioxidants like Polyphenol. Antioxidants help repair damage done to the body's cells by Free Radicals, (unstable oxygen molecules associated with cancer, heart disease and the effects of aging).

WASHINGTON --Pomegranate juice showed cardiovascular benefits in both laboratory mice and in cultured human coronary artery endothelial cells, according to a study published March 21, online ahead of print, in Proceedings of the National Academy of Sciences (www.pnas.org). The scientists reported antioxidant-rich pomegranate juice reduced progression of atherosclerosis by at least 30 percent in mice who were bred to have high cholesterol. Similarly, the cultured heart cells treated with the juice had a 50-percent increase in nitric oxide production, which helps blood vessels relax.
Lactoferrin
Lactoferrin is a minor glycoprotein component of whey. It belongs to the iron transporter or transferrin family of glycoproteins. Lactoferrin is also found in exocrime secretions from mammals and is released from neutrophil granules during inflammation. The lactoferrin concentration in bovine (cows) milk is only 0.5% to 1.0% while human breast milk can contain as much as 15% lactoferrin.
Lactoferrin plays several important roles in human biology. First, Lactoferrin is believed to play a role in the uptake and absorption of iron through the intestinal mucosa. It may be the primary or sole source of iron for breast fed infants. Second, Lactoferrin appears to have antibacterial, antiviral, antifungal, anti-inflammatory, antioxidant and immunomodulatory activities.
How Lactoferrin Works
Receptors for lactoferrin are found in monocytes, lymphocytes, neutrophils, intestinal tissue and one certain bacteria. Lactoferrins ability to bind iron may account for some of its anti-bacterial activity. Iron is essential to support the growth of pathogenic bacteria. Lactoferrin may also inhibit the attachment of bacteria to the intestinal wall.

1. The possible antiviral activity of supplemental lactoferrin may be due to its inhibition of virus-cell fusion and viral entry into cells. It is believed that Lactoferrin may promote the growth and differentiation of T lymphocytes. Lactoferrin appears to bind uniquely to sites on the T4 (helper) and T8 (suppressor) lymphocytes. Lactoferrin also appears to play a role in the regulation of cytokines and lymphokines, such as tumor necrosis (TNF)-alpha and interleukin (IL)-6.

Lactoferrin's possible antioxidant activity may also contribute to its possible immunomodulatory activity. Antioxidants are getting increasing attention as possible therapeutic agents in infections and a variety of other diseases. Lactoferrin's ability to bind iron probably contributes to both its antioxidant properties and its antibacterial action. Free iron is a contributor in the generation of free radicals.
Lactoferrin Research Summary
Lactoferrin, a natural occurring cytokine in the human body, has exhibited significant activity against Escherichia coli, Proteus mirabilis, Staphyloccocus aureus, Candida albicans, HIV, herpes simplex type 1, hepatitis C, cytomegalovirus and other pathogens in vitro (in a lab dish) studies. Human studies, however, are almost entirely lacking.

Grape juice

Grapes contain beneficial compounds called flavonoids, which are phytochemicals that give the vibrant purple color to grapes, grape juice and red wine; the stronger the color, the higher the concentration of flavonoids.

These flavonoid compounds as well as a second flavonoid-type compound (falling into the chemical category of stilbenes), Both compounds appear to decrease the risk of heart disease by:
Reducing platelet clumping and harmful blood clots
Protecting LDL cholesterol from the free radical damage that initiates LDL's artery-damaging actions.
In a study in which blood samples were drawn from 20 healthy volunteers both before and after they drank grape juice, researchers found several beneficial effects from their juice consumption.
First, an increase occurred in levels of nitric oxide, a compound produced in the body that helps reduce the formation of clots in blood vessels. Second, a decrease occured in platelet aggregation, or blood clotting, by red blood cells. Lastly, researchers saw an increase in levels of alpha-tocopherol, an antioxidant compound that is a member of the same family to which vitamin E belongs, and this increase was accompanied by a 50% increase in plasma antioxidant activity.
These findings confirmed the benefits found in an earlier study, where researchers found not only an increase in blood antioxidant activity, but also discovered that grape juice protected LDL cholesterol from oxidation, which turns LDL into an artery-damaging molecule. (Although LDL is often called the "bad" form of cholesterol, it is actually benign and only becomes harmful after it is damaged by free radicals or "oxidized.") Additionally, investigators have found that phenolic compounds in grape skins inhibit protein tyrosine kinases, a group of enzymes that play a key role in cell regulation. Compounds that inhibit these enzymes also suppress the production of a protein that causes blood vessels to constrict, thus reducing the flow of oxygen to the heart. This protein, called endothelin-1, is thought to be a key contributing agent in the development of heart disease.
Vitamin C
Vitamin C, or ascorbic acid, is a white, crystalline, water-soluble substance found in citrus fruits and green vegetables. As an antioxidant, vitamin C scavenges free radicals in the body and protects tissues from oxidative stress. Vitamin C also promotes the absorption of iron, while preventing its oxidation. Vitamin C is a vital cofactor to the formation of collagen, the connective tissue that supports arterial walls, skin, bones, and teeth. More vitamin C is contained in the adrenal glands than any other organ in the body and is required at higher levels during times of stress. Physical stresses on the body such as ingestion of heavy metals. cigarette smoking, infections, extreme temperatures, and chronic use of certain medications such as aspirin also signal the need for increased intake of vitamin C.

Ascorbic acid is one of the important and essential vitamins for human health. It is a water soluble vitamin. Most plants and animals synthesize ascorbic acid for their own requirement. However, apes and humans can not synthesize ascorbic acid due to lack of an enzyme gulonolactone oxidase. Hence, ascorbic acid has to be supplemented mainly through fruits, vegetables and tablets.

Stress, smoking, infections and burns deplete the ascorbic acid reserves in the body and demands higher doses of ascorbic acid supplementation. Based on available biochemical, clinical and epidemiological studies, the current RDA for ascorbic acid is suggested to be 100–120 mg/day to achieve cellular saturation and optimum risk reduction of heart diseases, stroke and cancer in healthy individuals. In view of its antioxidant property, ascorbic acid and its derivatives are widely used as preservatives in food industry. Many health benefits have been attributed to ascorbic acid namely antioxidant, anti-atherogenic and anti-carcinogenic activity.

“Any statements made here have not been evaluated by the Food & Drug Administration.
These products are not intended to cure, treat or prevent disease. No health claims are made for these products.”

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